Life-Threatening Subglottic Stenosis of Granulomatosis with Polyangiitis: A Case Report.
Jin AnJae Won SongPublished in: Medicina (Kaunas, Lithuania) (2021)
Granulomatosis with polyangiitis (GPA) is an autoimmune disease characterized by necrotizing granulomatous inflammation. Subglottic stenosis, which is defined as narrowing of the airway below the vocal cords, has a frequency of 16-23% in GPA. Herein, we present the case of a 39-year-old woman with subglottic stenosis manifesting as life-threatening GPA, which was recurrent under systemic immunosuppressive therapy. The patient underwent an emergency tracheostomy, intratracheal intervention, such as carbon dioxide (CO2) laser surgery and intralesional steroid injection via laryngomicroscopic surgery, and laryngotracheal resection with remodeling. Severe subglottic stenosis treatment requires active intratracheal intervention, surgery, and systemic immunosuppressive therapy.
Keyphrases
- minimally invasive
- coronary artery bypass
- carbon dioxide
- randomized controlled trial
- surgical site infection
- oxidative stress
- public health
- emergency department
- early onset
- stem cells
- drug induced
- acute coronary syndrome
- rheumatoid arthritis
- idiopathic pulmonary fibrosis
- percutaneous coronary intervention
- mechanical ventilation
- bone marrow
- coronary artery disease
- combination therapy
- acute respiratory distress syndrome
- replacement therapy
- emergency medical