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Effectiveness of two doses of Euvichol-plus oral cholera vaccine in response to the 2017/2018 outbreak: a matched case-control study in Lusaka, Zambia.

Cephas SialubanjeMuzala KapinaOrbrie CheweBelem Blamwell MatapoAlbertina Ngomah MoraesBrittany GianettiWilliam NgosaMpanga KasondeKunda MusondaModest MulengaC MicheloNyambe SinyangePatricia BoboKhozya ZyamboLucy MazyangaNathan BakyaitaVictor M Mukonka
Published in: BMJ open (2022)
These findings show that two doses of Euvichol-plus OCV are effective in a cholera outbreak setting in Lusaka, Zambia. The findings also indicate that two doses are more effective than a single dose and thus support the use of two doses of the vaccine as part of an integrated intervention to cholera control during outbreaks.
Keyphrases
  • randomized controlled trial
  • systematic review