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Upregulation of RGS2: a new mechanism for pirfenidone amelioration of pulmonary fibrosis.

Yan XieHaihong JiangQian ZhangSuneet MehrotraPeter W AbelMyron L ToewsDennis W WolffStephen RennardReynold A PanettieriThomas B CasaleYaping Tu
Published in: Respiratory research (2016)
Endogenous RGS2 exhibits anti-fibrotic functions. Upregulated RGS2 contributes significantly to the anti-fibrotic effects of pirfenidone.
Keyphrases
  • pulmonary fibrosis
  • idiopathic pulmonary fibrosis
  • systemic sclerosis
  • cell proliferation
  • poor prognosis
  • signaling pathway