High-level MYC expression associates with poor survival in patients with acute myeloid leukemia and collaborates with overexpressed p53 in leukemic transformation in patients with myelodysplastic syndrome.
Linlin GaoAzhar SaeedShivani GolemDa ZhangJanet WoodroofJoseph McGuirkSiddhartha GangulySunil AbhyankarTara L LinWei CuiPublished in: International journal of laboratory hematology (2020)
High-level MYC expression associates with p53 abnormality and poor survival in AML. MYC may provide proliferative advantage for leukemic progression in p53 dependent and independent manner.