Mineralocorticoid Receptor Antagonism Prevents Aortic Plaque Progression and Reduces Left Ventricular Mass and Fibrosis in Patients With Type 2 Diabetes and Chronic Kidney Disease: The MAGMA Trial.
Sanjay RajagopalanMirela A DobreJean-Eudes DazardArmando Vergara-MartelKim ConnellyMichael E FarkouhJuan GaztanagaHeather CongerAnn DeverLaleh Razavi-NematollahiAnas FaresGabriel Tensol Rodrigues PereiraJonnelle M EdwardsMark J CameronCheryl CameronSadeer G Al-KindiRobert D BrookBertram PittMatthew R WeirPublished in: Circulation (2024)
URL: https://www.clinicaltrials.gov; Unique identifier: NCT02169089.
Keyphrases
- left ventricular
- chronic kidney disease
- end stage renal disease
- phase iii
- hypertrophic cardiomyopathy
- study protocol
- aortic stenosis
- cardiac resynchronization therapy
- heart failure
- aortic valve
- acute myocardial infarction
- coronary artery disease
- mitral valve
- clinical trial
- phase ii
- left atrial
- pulmonary artery
- mouse model
- randomized controlled trial
- liver fibrosis
- peritoneal dialysis
- open label
- binding protein
- transcatheter aortic valve replacement
- coronary artery
- acute coronary syndrome
- percutaneous coronary intervention