A genome-wide association study identifying single nucleotide polymorphisms in the PPFIBP2 gene was predictive for interstitial lung disease in rheumatoid arthritis patients.
Tomoyuki KamenagaTsukasa MatsubaraKoji FukudaToshihisa MaedaKeiko FunahashiMarowa HashimotoYoshinori TakashimaKenichi KikuchiMasahiro FujitaTomoyuki MatsumotoRyosuke KurodaPublished in: Rheumatology advances in practice (2022)
could be a useful genetic marker for occurrence of interstitial pneumonia in RA patients and might help to identify the risk of ILD occurrence before RA treatment, thereby improving patient outcomes.
Keyphrases
- interstitial lung disease
- systemic sclerosis
- rheumatoid arthritis
- rheumatoid arthritis patients
- disease activity
- genome wide association study
- end stage renal disease
- idiopathic pulmonary fibrosis
- risk assessment
- ejection fraction
- genome wide
- newly diagnosed
- chronic kidney disease
- copy number
- peritoneal dialysis
- ankylosing spondylitis
- prognostic factors
- dna methylation
- extracorporeal membrane oxygenation
- transcription factor
- patient reported outcomes
- respiratory failure
- community acquired pneumonia