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Cardiac glycosides cause cytotoxicity in human macrophages and ameliorate white adipose tissue homeostasis.

Antoni OlonaCharlotte HateleyAna GuerreroJeong-Hun KoMichael R JohnsonParas K AnandDavid ThomasJesus GilJacques Behmoaras
Published in: British journal of pharmacology (2021)
The use of nanomolar concentration of cardiac glycosides could be an attractive therapeutic treatment for metabolic syndrome, characterized by pathogenic infiltration and activation of macrophages.
Keyphrases
  • adipose tissue
  • metabolic syndrome
  • left ventricular
  • insulin resistance
  • endothelial cells
  • high fat diet
  • induced pluripotent stem cells
  • uric acid
  • cardiovascular disease
  • pluripotent stem cells
  • combination therapy