Double-Blind Comparison of the Two Hallucinogens Dextromethorphan and Psilocybin: Experience-Dependent and Enduring Psychological Effects in Healthy Volunteers.

David S MathaiSamantha HilbertNathan D SepedaJustin C StricklandRoland R GriffithsAlbert Garcia-Romeu

Published in: Psychedelic medicine (New Rochelle, N.Y.) (2023)

This analysis suggests the utility of exploring clinical applications of dissociatives that occur within the supportive contexts that are characteristic of psychedelic research and that prioritize the optimization of psychologically valuable drug experiences. This study was registered with ClinicalTrials.gov (NCT02033707).

Keyphrases

double blind
clinical trial
mental health
placebo controlled
emergency department
randomized controlled trial
physical activity
phase ii
data analysis
electronic health record