Energy partitioning between fat and bone mass is controlled via a hypothalamic leptin/NPY relay.
Nicola J LeeYue QiRonaldo F EnriquezIreni ClarkeChi Kin IpNatalie WeePaul A BaldockHerbert HerzogPublished in: International journal of obesity (2005) (2020)
Taken together, these results demonstrate that leptin signaling in NPY neurons is critical for coordinating energy partitioning between fat and bone mass especially during situations of changes in energy balance.