Energy partitioning between fat and bone mass is controlled via a hypothalamic leptin/NPY relay.

Nicola J LeeYue QiRonaldo F EnriquezIreni ClarkeChi Kin IpNatalie WeePaul A BaldockHerbert Herzog

Published in: International journal of obesity (2005) (2020)

Taken together, these results demonstrate that leptin signaling in NPY neurons is critical for coordinating energy partitioning between fat and bone mass especially during situations of changes in energy balance.

Keyphrases

adipose tissue
bone mineral density
spinal cord
fatty acid
bone loss
bone regeneration
spinal cord injury