Discovery of canine drug toceranib phosphate as a repurposed agent against human hepatocellular carcinoma.

Ling QiaoSiyuan QinNingna WengBowen LiMaochao LuoZhe ZhangLi ZhouDong WangCanhua Huang

Published in: Liver international : official journal of the International Association for the Study of the Liver (2023)

Our results elucidate a newly identified therapeutic potential of TOC in treating HCC, sparking a growing interest in repurposing such canine drugs for human use.

Keyphrases

endothelial cells
induced pluripotent stem cells
pluripotent stem cells
small molecule
high throughput
drug induced
electronic health record