Serum cortisol and neuroticism for post-traumatic stress disorder over 2 years in patients with physical injuries.

Jae-Min KimHee-Ju KangJu-Wan KimHyunseok JangJung-Chul KimByung Jo ChunJu-Yeon LeeSung Wan KimIl-Seon Shin

Published in: Psychiatry and clinical neurosciences (2024)

Our findings reveal Neuroticism-dependent associations between serum cortisol levels and PTSD development, exhibiting temporal variations. These results suggest that PTSD development may be influenced by a complex, time-sensitive interplay of biological and psychosocial factors, underscoring the importance of considering individual differences in stress reactivity and personality in PTSD research and treatment.

Keyphrases

social support
posttraumatic stress disorder
mental health
physical activity
depressive symptoms
single cell
dna methylation
combination therapy