Downregulation of circ-RAPGEF5 inhibits colorectal cancer progression by reducing the expression of polypeptide N-acetylgalactosaminyltransferase 3 (GALNT3).

Duo ChengFeifei ChuFang LiangNan ZhangJingjing WangWenli Yue

Published in: Environmental toxicology (2024)

These findings revealed that circ-RAPGEF5 played an oncogenic role through the miR-545-5p/GALNT3 axis in CRC progression, providing potential therapeutic targets for the treatment of CRC.

Keyphrases

poor prognosis
cell proliferation
single cell
binding protein
replacement therapy
smoking cessation