Platelets' RNA as biomarker trove for differentiation of early-stage hepatocellular carcinoma from underlying cirrhotic nodules.

Published in: PloS one (2021)

Our study reports liquid biopsy-based platelets mRNA signature for early diagnosis of HCC from underlying cirrhotic nodules. Moreover, differential expression of CD41+ platelets in two groups provides new insights into a probable link between CD41 expression on platelets with the progression of cirrhosis to HCC.

Keyphrases

early stage
poor prognosis
red blood cell
binding protein
emergency department
squamous cell carcinoma
ionic liquid
ultrasound guided
radiation therapy
adverse drug
fine needle aspiration