Upstream regulation for initiation of restricted Shh expression in the chick limb bud.

Haruka MatsubaraDaisuke SaitoGembu Abe Hitoshi YokoyamaTakayuki SuzukiKoji Tamura

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2017)

Taken together with results of functional assays, we propose a model in which positive and negative transcriptional regulatory networks accumulate their functions in the intersection area of their expression regions to provide a restricted spot for the ZPA, the source of morphogen, Shh. Developmental Dynamics 246:417-430, 2017. © 2017 Wiley Periodicals, Inc.

Keyphrases

poor prognosis
transcription factor
gene expression
binding protein
oxidative stress
heat shock protein