miR-26 deficiency causes alterations in lens transcriptome and results in adult-onset cataract.

Anil Upreti Thanh V HoangMinghua LiJared A TangemanDavid S DierkerBrad D WagnerPanagiotis A TsonisChun LiangSalil A Lachke Michael L Robinson

Published in: bioRxiv : the preprint server for biology (2024)

miR-1, miR-184 and miR-26 are each dispensable for normal embryonic lens development. However, loss of miR-26 causes lens transcriptome changes and drives cataract formation.

Keyphrases

cell proliferation
long non coding rna
long noncoding rna
gene expression
cataract surgery
rna seq
genome wide