Salil A Lachke

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 31

Top Topics

Binding Protein

Cataract Surgery

Genome Wide Identification

Top Venues

Development (Cambridge, England)

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Jared A Tangeman, Sofia M Rebull, Erika Grajales-Esquivel, Jacob M Weaver, Stacy Bendezu-Sayas, Michael L Robinson, Salil A Lachke, Katia Del Rio-Tsonis
Integrated single-cell multiomics uncovers foundational regulatory mechanisms of lens development and pathology. Development (Cambridge, England) 151 (1) (2024)
Anil Upreti, Thanh V Hoang, Minghua Li, Jared A Tangeman, David S Dierker, Brad D Wagner, Panagiotis A Tsonis, Chun Liang, Salil A Lachke, Michael L Robinson
miR-26 deficiency causes alterations in lens transcriptome and results in adult-onset cataract. bioRxiv : the preprint server for biology (2024)
Jared A Tangeman, Sofia M Rebull, Erika Grajales-Esquivel, Jacob M Weaver, Stacy Bendezu-Sayas, Michael L Robinson, Salil A Lachke, Katia Del Rio-Tsonis
Integrated single-cell multiomics uncovers foundational regulatory mechanisms of lens development and pathology. Development (Cambridge, England) 151 (1) (2024)
Anil Upreti, Thanh V Hoang, Minghua Li, Jared A Tangeman, David S Dierker, Brad D Wagner, Panagiotis A Tsonis, Chun Liang, Salil A Lachke, Michael L Robinson
miR-26 deficiency causes alterations in lens transcriptome and results in adult-onset cataract. bioRxiv : the preprint server for biology (2024)
Anil Upreti, Stephanie L Padula, Jacob M Weaver, Brad D Wagner, Allison M Kneller, Anthony L Petulla, Salil A Lachke, Michael L Robinson
A Transcriptomics Analysis of the Regulation of Lens Fiber Cell Differentiation in the Absence of FGFRs and PTEN. Cells 13 (14) (2024)
Jared A Tangeman, Sofia M Rebull, Erika Grajales-Esquivel, Jacob M Weaver, Stacy Bendezu-Sayas, Michael L Robinson, Salil A Lachke, Katia Del Rio-Tsonis
Integrated single-cell multiomics uncovers foundational regulatory mechanisms of lens development and pathology. Development (Cambridge, England) 151 (1) (2024)
Anil Upreti, Stephanie L Padula, Jacob M Weaver, Brad D Wagner, Allison M Kneller, Anthony L Petulla, Salil A Lachke, Michael L Robinson
A Transcriptomics Analysis of the Regulation of Lens Fiber Cell Differentiation in the Absence of FGFRs and PTEN. Cells 13 (14) (2024)
Jared A Tangeman, Sofia M Rebull, Erika Grajales-Esquivel, Jacob M Weaver, Stacy Bendezu-Sayas, Michael L Robinson, Salil A Lachke, Katia Del Rio-Tsonis
Integrated single-cell multiomics uncovers foundational regulatory mechanisms of lens development and pathology. Development (Cambridge, England) 151 (1) (2024)
Jared A Tangeman, Sofia M Rebull, Erika Grajales-Esquivel, Jacob M Weaver, Stacy Bendezu-Sayas, Michael L Robinson, Salil A Lachke, Katia Del Rio-Tsonis
Integrated single-cell multiomics uncovers foundational regulatory mechanisms of lens development and pathology. Development (Cambridge, England) 151 (1) (2024)
Anil Upreti, Stephanie L Padula, Jacob M Weaver, Brad D Wagner, Allison M Kneller, Anthony L Petulla, Salil A Lachke, Michael L Robinson
A Transcriptomics Analysis of the Regulation of Lens Fiber Cell Differentiation in the Absence of FGFRs and PTEN. Cells 13 (14) (2024)
Jared A Tangeman, Sofia M Rebull, Erika Grajales-Esquivel, Jacob M Weaver, Stacy Bendezu-Sayas, Michael L Robinson, Salil A Lachke, Katia Del Rio-Tsonis
Integrated single-cell multiomics uncovers foundational regulatory mechanisms of lens development and pathology. Development (Cambridge, England) 151 (1) (2024)
Jared A Tangeman, Sofia M Rebull, Erika Grajales-Esquivel, Jacob M Weaver, Stacy Bendezu-Sayas, Michael L Robinson, Salil A Lachke, Katia Del Rio-Tsonis
Integrated single-cell multiomics uncovers foundational regulatory mechanisms of lens development and pathology. Development (Cambridge, England) 151 (1) (2024)
Jared A Tangeman, Sofia M Rebull, Erika Grajales-Esquivel, Jacob M Weaver, Stacy Bendezu-Sayas, Michael L Robinson, Salil A Lachke, Katia Del Rio-Tsonis
Integrated single-cell multiomics uncovers foundational regulatory mechanisms of lens development and pathology. bioRxiv : the preprint server for biology (2023)
Archana D Siddam, Matthieu Duot, Sarah Y Coomson, Deepti Anand, Sandeep Aryal, Bailey A T Weatherbee, Yann Audic, Luc Paillard, Salil A Lachke
High-Throughput Transcriptomics of Celf1 Conditional Knockout Lens Identifies Downstream Networks Linked to Cataract Pathology. Cells 12 (7) (2023)
Matthieu Duot, Roselyne Viel, Justine Viet, Catherine Le Goff-Gaillard, Luc Paillard, Salil A Lachke, Carole Gautier-Courteille, David Reboutier
Eye Lens Organoids Made Simple: Characterization of a New Three-Dimensional Organoid Model for Lens Development and Pathology. Cells 12 (20) (2023)
Sandeep Aryal, Deepti Anand, Hongzhan Huang, Ashok P Reddy, Phillip A Wilmarth, Larry L David, Salil A Lachke
Proteomic profiling of retina and retinal pigment epithelium combined embryonic tissue to facilitate ocular disease gene discovery. Research square (2023)
Sandeep Aryal, Deepti Anand, Hongzhan Huang, Ashok P Reddy, Phillip A Wilmarth, Larry L David, Salil A Lachke
Proteomic profiling of retina and retinal pigment epithelium combined embryonic tissue to facilitate ocular disease gene discovery. Human genetics (2023)
Anil Upreti, Stephanie L Padula, Jared A Tangeman, Brad D Wagner, Michael J O'Connell, Tycho J Jaquish, Raye K Palko, Courtney J Mantz, Deepti Anand, Frank J Lovicu, Salil A Lachke, Michael L Robinson
Lens Epithelial Explants Treated with Vitreous Humor Undergo Alterations in Chromatin Landscape with Concurrent Activation of Genes Associated with Fiber Cell Differentiation and Innate Immune Response. Cells 12 (3) (2023)
Anil Upreti, Stephanie L Padula, Jared A Tangeman, Brad D Wagner, Michael J O'Connell, Tycho J Jaquish, Raye K Palko, Courtney J Mantz, Deepti Anand, Frank J Lovicu, Salil A Lachke, Michael L Robinson
Lens Epithelial Explants Treated with Vitreous Humor Undergo Alterations in Chromatin Landscape with Concurrent Activation of Genes Associated with Fiber Cell Differentiation and Innate Immune Response. Cells 12 (3) (2023)
Anil Upreti, Stephanie L Padula, Jared A Tangeman, Brad D Wagner, Michael J O'Connell, Tycho J Jaquish, Raye K Palko, Courtney J Mantz, Deepti Anand, Frank J Lovicu, Salil A Lachke, Michael L Robinson
Lens Epithelial Explants Treated with Vitreous Humor Undergo Alterations in Chromatin Landscape with Concurrent Activation of Genes Associated with Fiber Cell Differentiation and Innate Immune Response. Cells 12 (3) (2023)
Matthieu Duot, Roselyne Viel, Justine Viet, Catherine Le Goff-Gaillard, Luc Paillard, Salil A Lachke, Carole Gautier-Courteille, David Reboutier
Eye lens organoids going simple: characterization of a new 3-dimensional organoid model for lens development and pathology. bioRxiv : the preprint server for biology (2023)
Anil Upreti, Stephanie L Padula, Jared A Tangeman, Brad D Wagner, Michael J O'Connell, Tycho J Jaquish, Raye K Palko, Courtney J Mantz, Deepti Anand, Frank J Lovicu, Salil A Lachke, Michael L Robinson
Lens Epithelial Explants Treated with Vitreous Humor Undergo Alterations in Chromatin Landscape with Concurrent Activation of Genes Associated with Fiber Cell Differentiation and Innate Immune Response. Cells 12 (3) (2023)
Lauren E Blizzard, Chelsea Menke, Shaili D Patel, Ronald R Waclaw, Salil A Lachke, Rolf W Stottmann
A Novel Mutation in Cse1l Disrupts Brain and Eye Development with Specific Effects on Pax6 Expression. Journal of developmental biology 9 (3) (2021)
Helene Choquet, Ronald B Melles, Deepti Anand, Jie Yin, Gabriel Cuellar-Partida, Wei Wang, null null, Thomas J Hoffmann, K Saidas Nair, Pirro G Hysi, Salil A Lachke, Eric Jorgensen
A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nature communications 12 (1) (2021)
Sandeep Aryal, Justine Viet, Bailey A T Weatherbee, Archana D Siddam, Francisco G Hernandez, Carole Gautier-Courteille, Luc Paillard, Salil A Lachke
The cataract-linked RNA-binding protein Celf1 post-transcriptionally controls the spatiotemporal expression of the key homeodomain transcription factors Pax6 and Prox1 in lens development. Human genetics 139 (12) (2020)
Sandeep Aryal, Deepti Anand, Francisco G Hernandez, Bailey A T Weatherbee, Hongzhan Huang, Ashok P Reddy, Phillip A Wilmarth, Larry L David, Salil A Lachke
MS/MS in silico subtraction-based proteomic profiling as an approach to facilitate disease gene discovery: application to lens development and cataract. Human genetics 139 (2) (2019)
Timothy C Cox, Andrew C Lidral, Jason C McCoy, Huan Liu, Liza L Cox, Ying Zhu, Ryan D Anderson, Lina M Moreno Uribe, Deepti Anand, Mei Deng, Chika T Richter, Nichole L Nidey, Jennifer M Standley, Elizabeth E Blue, Jessica X Chong, Joshua D Smith, Edwin P Kirk, Hanka Venselaar, Katy N Krahn, Hans van Bokhoven, Huiqing Zhou, Robert A Cornell, Ian A Glass, Michael J Bamshad, Deborah A Nickerson, Jeffrey C Murray, Salil A Lachke, Thomas B Thompson, Michael F Buckley, Tony Roscioli
Mutations in GDF11 and the extracellular antagonist, Follistatin, as a likely cause of Mendelian forms of orofacial clefting in humans. Human mutation 40 (10) (2019)
Stephanie L Padula, Deepti Anand, Thanh V Hoang, Blake R Chaffee, Lin Liu, Chun Liang, Salil A Lachke, Michael L Robinson
High-throughput transcriptome analysis reveals that the loss of Pten activates a novel NKX6-1/RASGRP1 regulatory module to rescue microphthalmia caused by Fgfr2-deficient lenses. Human genetics 138 (11-12) (2019)
Deepti Anand, Atul Kakrana, Archana D Siddam, Hongzhan Huang, Irfan Saadi, Salil A Lachke
RNA sequencing-based transcriptomic profiles of embryonic lens development for cataract gene discovery. Human genetics 137 (11-12) (2018)
Deepti Anand, Smriti A Agrawal, Anne Slavotinek, Salil A Lachke
Mutation update of transcription factor genes FOXE3, HSF4, MAF, and PITX3 causing cataracts and other developmental ocular defects. Human mutation 39 (4) (2018)
Archana D Siddam, Carole Gautier-Courteille, Linette Perez-Campos, Deepti Anand, Atul Kakrana, Christine A Dang, Vincent Legagneux, Agnès Méreau, Justine Viet, Jeffrey M Gross, Luc Paillard, Salil A Lachke
The RNA-binding protein Celf1 post-transcriptionally regulates p27Kip1 and Dnase2b to control fiber cell nuclear degradation in lens development. PLoS genetics 14 (3) (2018)