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In-vitro validated methods for encoding digital data in deoxyribonucleic acid (DNA).

Golam Md MortuzaJorge GuerreroShoshanna LlewellynMichael D TobiasonGeorge D DickinsonWilliam L HughesReza ZadeganTim Andersen
Published in: BMC bioinformatics (2023)
Deoxyribonucleic acid (DNA) is emerging as an alternative archival memory technology. Recent advancements in DNA synthesis and sequencing have both increased the capacity and decreased the cost of storing information in de novo synthesized DNA pools. In this survey, we review methods for translating digital data to and/or from DNA molecules. An emphasis is placed on methods which have been validated by storing and retrieving real-world data via in-vitro experiments.
Keyphrases
  • circulating tumor
  • cell free
  • single molecule
  • electronic health record
  • nucleic acid
  • big data
  • working memory
  • cross sectional
  • data analysis
  • machine learning