What can intracoronary pressure measurements tell us about flow reserve? Pressure-Bounded coronary flow reserve and example application to the randomized DEFER trial.
Frederik M ZimmermannNico H J PijlsBernard De BruyneG Jan-Willem BechPepijn van SchaardenburghRichard L KirkeeideK Lance GouldNils P JohnsonPublished in: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions (2017)
pb-CFR offers a new method for studying FFR/CFR discordances using regular pressure wire measurements. As an example application, DEFER suggested that low pb-CFR with high FFR may be a risk marker for more angina and worse outcomes, but that this risk cannot be modified by revascularization. © 2017 Wiley Periodicals, Inc.
Keyphrases
- coronary artery disease
- coronary artery
- heavy metals
- phase iii
- percutaneous coronary intervention
- phase ii
- open label
- clinical trial
- double blind
- coronary artery bypass grafting
- type diabetes
- placebo controlled
- randomized controlled trial
- metabolic syndrome
- acute coronary syndrome
- insulin resistance
- skeletal muscle
- aqueous solution
- left ventricular
- atrial fibrillation
- weight loss