High versus low positive end-expiratory pressure setting in patients receiving veno-venous extracorporeal membrane oxygenation support for severe acute respiratory distress syndrome: study protocol for the multicentre, randomised ExPress SAVER Trial.

Mitsuaki NishikimiShinichiro OhshimoJun HamaguchiKenji FujizukaYoshihiro HagiwaraTatsuhiko AnzaiJunki IshiiYoshitaka OgataToshiyuki AokageTokuji IkedaTsukasa YagiGinga SuzukiKen IshikuraKen KatsutaDaisuke KonnoNoriyuki HattoriTomoyuki NakamuraYosuke MatsumuraDaisuke KasugaiHitoshi KikuchiTatsuhiko IinoShinichi KaiHaruka HashimotoTakeshi YoshidaYumi IgarashiTakayuki OguraKazuki MatsumuraKeiki ShimizuMitsunobu NakamuraShingo IchibaKunihiko TakahashiNobuaki Shime

Published in: BMJ open (2023)

28 March 2023, version 4.0.

Keyphrases

extracorporeal membrane oxygenation
acute respiratory distress syndrome
study protocol
mechanical ventilation
clinical trial
double blind
phase iii
open label
phase ii
randomized controlled trial
respiratory failure
placebo controlled
psychometric properties
early onset
intensive care unit
drug induced