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Extracapsular invasion: A potential prognostic marker for Carcinoma ex-pleomorphic adenoma of the salivary glands? A Systematic Review.

Everton Freitas de MoraisJuliana Campos PinheiroDáurea Adília Cóbe SenaHébel Cavalcanti GalvãoLélia Batista de SouzaRoseana de Almeida Freitas
Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2019)
This systematic review demonstrates the importance of evaluating extracapsular invasion in cases diagnosed as CXPA, considering that tumours with invasion >1.5 mm, regardless of histopathological subtype, are associated with a worse prognosis. It is important to analyse the extracapsular invasion, especially as an auxiliary method to assess the prognosis of cases diagnosed in the initial clinical stages, thus identifying the possible biological behaviour of the neoplastic process and guiding the most appropriate patient management.
Keyphrases
  • cell migration
  • systematic review
  • randomized controlled trial
  • risk assessment
  • climate change