Visible-Light-Induced para -Difluoroalkylation of Aniline Derivatives.

Visible-light-induced, iridium catalyzed, para -selective C-H difluoroalkylation of aniline derivatives under mild reaction conditions is reported. Various substrates and bioactive compounds, such as precursors of vorinostat and chlorpropham, were all well tolerated. This protocol features a wide substrate scope, high regioselectivity, low catalyst usage, and operational simplicity.