DACRA induces profound weight loss, satiety control, and increased mitochondrial respiratory capacity in adipose tissue.
Emilie A PetersenIda BlomSimone A MelanderMays Al-RubaiMarina VidottoLouise Torp DalgaardMorten A KarsdalKim HenriksenSteen LarsenAnna Thorsø LarsenPublished in: International journal of obesity (2005) (2024)
These findings demonstrate favorable effects of KBP-336 on MRC in adipose tissue, indicating an increased energy expenditure and capacity to utilize fatty acids. Thus, providing more mechanistic insight into the DACRA-induced weight loss.
Keyphrases
- weight loss
- adipose tissue
- bariatric surgery
- roux en y gastric bypass
- fatty acid
- insulin resistance
- high fat diet
- gastric bypass
- oxidative stress
- high glucose
- diabetic rats
- intellectual disability
- glycemic control
- obese patients
- weight gain
- endothelial cells
- type diabetes
- skeletal muscle
- respiratory tract
- physical activity
- body mass index