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Efficacy and safety of ketamine-assisted electroconvulsive therapy in major depressive episode: a systematic review and network meta-analysis.

Taeho Greg RheeSung Ryul ShimJonah H PoppThomas A TrikalinosRobert A RosenheckCharles H KellnerStephen J SeinerRandall T EspinozaBrent P ForesterRoger S McIntyre
Published in: Molecular psychiatry (2023)
Ketamine-assisted ECT is tolerable and may be efficacious in improving depressive symptoms, but a relative adverse impact on cognition may be an important clinical consideration. Anesthetic agents should be considered based on patient profiles and/or preferences to improve effectiveness and safety of ECT use.
Keyphrases
  • depressive symptoms
  • pain management
  • case report
  • bipolar disorder
  • social support
  • mild cognitive impairment
  • white matter
  • stress induced
  • decision making
  • physical activity
  • adverse drug
  • electronic health record