Characterization of novel cell lines derived from a MYC-driven murine model of lethal metastatic adenocarcinoma of the prostate.

Mark C MarkowskiGretchen K HubbardJessica L HicksQizhi ZhengAlexia KingDavid EsopiApurv RegeSrinivasan YegnasubramanianCharles J BieberichAngelo M De Marzo

Published in: The Prostate (2018)

These cell lines are a novel model of androgen-insensitive prostatic adenocarcinoma driven by MYC over-expression and Pten loss.

Keyphrases

squamous cell carcinoma
benign prostatic hyperplasia
poor prognosis
prostate cancer
transcription factor
locally advanced
small cell lung cancer
cell proliferation
pi k akt
binding protein
long non coding rna
rectal cancer
signaling pathway