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Genome-wide association of individual vulnerability with alcohol-associated liver disease: A Korean genome and epidemiology study.

Kwang Yoon KimJung Oh KimYoung Sang KimJa-Eun ChoiJae-Min ParkKunhee HanDa-Hyun ParkYon Chul ParkBom Taeck KimKyung-Won Hong
Published in: Hepatology (Baltimore, Md.) (2021)
SNPs, including HNF1A rs1183910 minor allele, are the most promising genetic candidates for protection against ALD. The expression of genes contributing to ALD development may be altered by the amount of alcohol consumed.
Keyphrases
  • genome wide association
  • genome wide
  • poor prognosis
  • dna methylation
  • alcohol consumption
  • climate change
  • copy number
  • nuclear factor
  • long non coding rna
  • inflammatory response
  • transcription factor