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[Alzheimer disease and epilepsy].

A M TeplyshovaV K Datieva
Published in: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (2021)
Alzheimer Disease (AD) is a progressive neurodegenerative disorder characterized by loss of memory, difficulty in thinking, changes in behavior and personality disorders. The risk of developing epileptic seizures (ES) in patients with AD increases significantly. Animal and human studies have shown a close relationship between the pathogenesis of ES and AD. The exact prevalence of ES in AD remains unclear due to methodological difficulties, in particular, detection of ES in patients with cognitive impairment. EP types differ in sporadic and hereditary forms of AD. Antiepileptic therapy in AD has its own characteristics. Certain antiepileptic drugs can have a positive effect on cognitive function.
Keyphrases
  • cognitive impairment
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  • multiple sclerosis
  • stem cells
  • late onset
  • bone marrow
  • mesenchymal stem cells
  • early onset
  • pluripotent stem cells
  • cell therapy