Investigating the Role of BAFF and Its Receptors in Renal Transplant Recipients with Chronic Antibody-Mediated Rejection.

Shima Afzali Saeedeh Salehi Abbas Shahi Marzie Esmaeili Samad Farashi Bonab Azin Peykari Farzaneh Bagherpour Bita Ansaripour Tayebeh Soleimanian Fatemeh Pour-Reza-Gholi Ali Akbar Amirzargar

Published in: Journal of immunology research (2021)

Both soluble protein and mRNA transcript of BAFF increased in transplant recipients. However, BAFF neither at the serum level nor at the mRNA transcript level cannot be a good biomarker for the prediction of cAMR. In addition, expression of TACI, compared to other receptors of BAFF, confers a potential to be used in distinguishing cAMR and stable kidney transplant patients.

Keyphrases

binding protein
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
poor prognosis
rna seq
prognostic factors
small molecule
risk assessment
human health