miR-181c, a potential mediator for acute kidney injury in a burn rat model with following sepsis.
Chuanshu HuangXiao LiShaofang HanJingjie ZhangJing WangJiake ChaiPublished in: European journal of trauma and emergency surgery : official publication of the European Trauma Society (2022)
Our results demonstrated that miR-181c could suppress TLR4 expression, reduce inflammatory factor and chemokine secretion, mitigate inflammatory cell infiltration into the kidney and downregulate KIM-1 expression, which might ultimately attenuate burn sepsis-induced AKI.