Sumatriptan, a serotonin 5HT 1B receptor agonist, acutely reduces insulin secretion and sensitivity and glucose effectiveness in overweight humans: A double-blinded placebo-controlled cross-over trial.
Rajna GolubicMouhamad Hussein IsmailMasa JosipovicJane KennetAlfonso GalderisiMark L EvansPublished in: Diabetes, obesity & metabolism (2023)
receptors have a glucoregulatory role in humans, probably acting on insulin secretion, insulin sensitivity and glucose effectiveness.