Identification and evaluation of risk of generalizability biases in pilot versus efficacy/effectiveness trials: a systematic review and meta-analysis.
Michael W BeetsR Glenn WeaverJohn P A IoannidisMarco GeraciKeith BrazendaleLindsay DeckerAnthony D OkelyDavid LubansEsther van SluijsRussell JagoGabrielle Turner-McGrievyJames ThrasherXiaming LiAndrew J MilatPublished in: The international journal of behavioral nutrition and physical activity (2020)
Pre-emptive avoidance of RGBs during the initial testing of an intervention may diminish the voltage drop between pilot and larger efficacy/effectiveness trials and enhance the odds of successful translation.