Omega 3 Fatty Acids Attenuate the Acute Kidney Injury to CKD Transition and Renal Fibrosis: Identification of Antifibrotic Metabolites.

Kai Tokumaru Tadashi ImafukuTakao SatohTomoaki InazumiShu HirashimaAyano NishinoiriTaisei NagasakiHitoshi Maeda Yukihiko SugimotoMotoko TanakaKazutaka MatsushitaToru MaruyamaHiroshi Watanabe

Published in: Kidney360 (2024)

ω3PUFAs prevents AKI to CKD and renal fibrosis. Moreover, the EPA metabolites 18-HEPE, 17,18-EpETE and 17,18-diHETE were found to have antifibrotic effects.

Keyphrases

acute kidney injury
chronic kidney disease
ms ms
fatty acid
cardiac surgery
pulmonary fibrosis
liver fibrosis
mouse model