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Gene expression profiles in neurological tissues during West Nile virus infection: a critical meta-analysis.

Robin KoschJulien DelarocquePeter ClausStefanie C BeckerKlaus Jung
Published in: BMC genomics (2018)
A critical discussion of our findings shows benefits but also limitations of the meta-analytic approach. In summary, the produced gene lists, identified gene ontology terms and network reconstructions appear to be more reliable than the results from the individual studies. Our meta-analysis provides a basis for further research on the transcriptional mechanisms by WNV infections in neurological tissues.
Keyphrases
  • gene expression
  • systematic review
  • case control
  • meta analyses
  • dna methylation
  • genome wide
  • copy number
  • randomized controlled trial
  • computed tomography
  • oxidative stress
  • heat stress
  • genome wide analysis
  • heat shock