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Evolution of cisplatin resistance through coordinated metabolic reprogramming of the cellular reductive state.

Wangie YuYunyun ChenNagireddy PutluriAbdullah OsmanCristian CoarfaVasanta PutluriAbu H M KamalJennifer Kay AsmussenPanagiostis KatsonisJeffrey N MyersStephen Y LaiWuhao LuClifford C StephanReid T PowellFaye M JohnsonHeath D SkinnerJawad KaziKazi Mokim AhmedLinghao HuAddison ThreetMatthew D MeyerJames A BanksonTony WangJack DavisKirby R ParkerMadison A HarrisMokryun L BaekGloria V EcheverriaXiaoli QiJin WangAndy I FrederickAlex J WalshOlivier LichtargeMitchell J FrederickVlad C Sandulache
Published in: British journal of cancer (2023)
Our analysis identified coordinated metabolic changes associated with CDDP resistance that may provide new therapeutic avenues through targeting of these convergent pathways.
Keyphrases
  • cancer therapy