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Development of a strictly regulated xylose-induced expression system in Streptomyces.

Yuji NoguchiNorimasa KashiwagiAtsuko UzuraPrihardi KaharAkihiko KondoHaruo IkedaMasahiro Sota
Published in: Microbial cell factories (2018)
In this study, a strictly regulated protein expression system was developed based on a xylose-induced system. As far as we could ascertain, this is the first report of engineered inducible protein expression in Streptomyces by means of a xylose-induced system. This system might be applicable for controllable expression of toxic products or in the field of synthetic biology using Streptomyces strains.
Keyphrases
  • high glucose
  • diabetic rats
  • poor prognosis
  • drug induced
  • escherichia coli
  • transcription factor
  • saccharomyces cerevisiae
  • oxidative stress