The efficacy of GLP-1RAs for the management of postprandial hypoglycemia following bariatric surgery: a systematic review.
David C LlewellynHugh Logan EllisSimon J B AylwinEduard OštarijašShauna GreenWilliam SheridanNicholas W S ChewCarel W le RouxAlexander Dimitri MirasAmeet G PatelRoyce P VincentGeorgios K DimitriadishPublished in: Obesity (Silver Spring, Md.) (2022)
Postprandial hyperinsulinemic hypoglycemia remains a notoriously difficult to manage metabolic complication of bariatric surgery. This first, to the authors' knowledge, systematic review presents evidence suggesting that use of GLP-1RAs does not lead to an increase of hypoglycemic episodes, and, although this approach may appear counterintuitive, the findings suggest that GLP-1RAs could reduce the number of postprandial hypoglycemic episodes and improve glycemic variability.