Plant-Derived Exosome-like Nanoparticles for Biomedical Applications and Regenerative Therapy.
Andari SarasatiMuhammad Hidayat SyahruddinArchadian NuryantiIka Dewi AnaAnggraini BarlianChristofora Hanny WijayaDiah RatnadewiTriati Dewi Kencana WunguHiroshi TakemoriPublished in: Biomedicines (2023)
Plant-derived exosome-like nanoparticles (PDENs) comprise various bioactive biomolecules. As an alternative cell-free therapeutic approach, they have the potential to deliver nano-bioactive compounds to the human body, and thus lead to various anti-inflammatory, antioxidant, and anti-tumor benefits. Moreover, it is known that Indonesia is one of the herbal centers of the world, with an abundance of unexplored sources of PDENs. This encouraged further research in biomedical science to develop natural richness in plants as a source for human welfare. This study aims to verify the potential of PDENs for biomedical purposes, especially for regenerative therapy applications, by collecting and analyzing data from the latest relevant research and developments.
Keyphrases
- cell free
- endothelial cells
- anti inflammatory
- stem cells
- mesenchymal stem cells
- cell therapy
- induced pluripotent stem cells
- public health
- tissue engineering
- pluripotent stem cells
- drinking water
- risk assessment
- electronic health record
- climate change
- bone marrow
- cell wall
- human health
- machine learning
- replacement therapy
- circulating tumor