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Promotion and Mechanism of Acupotomy on Chondrocyte Autophagy in Knee Osteoarthritis Rabbits.

Man LuDe-Hong MengZe-Yu SheXian WuShuai XiaKai-Ning YangCun-Bin LiuTao LiYong-Hui Yang
Published in: Chinese journal of integrative medicine (2024)
Acupotomy could effectively up-regulate the expressions of AMPK, ULK1 and Beclin1, reduce the expression of mTOR, promote autophagy, and alleviate joint degeneration. Acupotomy is a promising complementary and alternative therapy for KOA.
Keyphrases
  • knee osteoarthritis
  • cell death
  • endoplasmic reticulum stress
  • signaling pathway
  • poor prognosis
  • oxidative stress
  • skeletal muscle
  • cell proliferation
  • binding protein
  • protein kinase