Phosphodiesterase 3 inhibitors do not influence lactate kinetics and clinical outcomes in patients with septic shock: A multicentre cohort study.

Sharon Tai-PassmannClaire A D SlegersPleun HemelaarNicole WaaldersMatty KoopmansBas van den BogaardMichiel van Lookeren CampagneJamilla GoedegebuurMarnix KuindersmaNicolas SchrotenFieke van der ElsenBart P X GradyWisse M F van den BeukenDorien KiersPeter PickkersHuub L A van den Oevernull null

Published in: Journal of critical care (2024)

No association was found between the administration of PDE3i and lactate kinetics, resolution of organ failure, ICU or hospital LOS or hospital mortality.

Keyphrases

septic shock
healthcare
acute care
intensive care unit

adverse drug
clinical trial
risk factors

study protocol
single molecule
randomized controlled trial

mechanical ventilation
cardiovascular disease
double blind