Ki67, CD105, and α-SMA Expression Supports Biological Distinctness of Oral Squamous Cell Carcinoma Arising in the Background of Oral Submucous Fibrosis.

Amol Ramchandra GadbailSheetal KordeMinal S ChaudharySachin Chakradhar SarodeShailesh M GondivkarRavi DandeSatyajit Ashok TekadeMonal YuwanatiAlka HandeShankaragouda Patil

Published in: Asian Pacific journal of cancer prevention : APJCP (2020)

Proliferation, neoangiogenesis and myofibroblast differentiation were significantly higher in the OSCC group compared to the OSCC-OSF group. This suggests the biological distinctness of OSCC-OSF, which could help the future development of targeted therapies.

Keyphrases

poor prognosis
signaling pathway
current status
transforming growth factor
neoadjuvant chemotherapy
squamous cell carcinoma
radiation therapy
liver fibrosis