Association of Autoantibodies against M2-Muscarinic Acetylcholine Receptor with Atrial Fibrosis in Atrial Fibrillation Patients.
Guiling MaXuejiao WuLi-Jun ZengJiawei JinXing-Peng LiuJianjun ZhangLin ZhangPublished in: Cardiology research and practice (2019)
Serum anti-M2-R levels are higher in AF patients and are associated with the severity of atrial fibrosis. In addition, serum anti-M2-R levels are positively correlated to TGF-β1 and CTGF expression in the left atrial appendage.
Keyphrases
- atrial fibrillation
- left atrial appendage
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- catheter ablation
- left atrial
- peritoneal dialysis
- prognostic factors
- poor prognosis
- systemic lupus erythematosus
- percutaneous coronary intervention
- acute coronary syndrome
- long non coding rna
- epithelial mesenchymal transition