Hepatitis C treatment program in Maputo, Mozambique, the challenge of genotypes and key populations: A 5-year retrospective analysis of routine programmatic data.
Anne LoarecAna Gabriela GutierrezGil MuvaleAleny CoutoAude NguyenSabine YerlyYolanda PintoNatercia MadeiraAlan GonzalesLucas MolfinoIza CigleneckiNatalia Tamayo AntabakPublished in: Health science reports (2023)
We found varied genotypes, including some identified as difficult-to-treat subtypes. People who used drugs were more likely to present genotype 1. In addition, opioid substitution therapy was key for these patients to achieve cure. Access to second-generation direct-acting antivirals (DAAs) and integration of HCV care with harm reduction are crucial to program effectiveness.
Keyphrases
- quality improvement
- end stage renal disease
- healthcare
- randomized controlled trial
- newly diagnosed
- ejection fraction
- pain management
- chronic kidney disease
- palliative care
- prognostic factors
- electronic health record
- systematic review
- stem cells
- machine learning
- mesenchymal stem cells
- artificial intelligence
- deep learning
- replacement therapy
- hiv infected
- antiretroviral therapy