Changes in Protease-Activated Receptor and Trypsin-1 Expression Are Involved in the Therapeutic Effect of Mg 2+ Supplementation in Type 2 Diabetes-Induced Gastric Injury in Male Adult Rats.
Nasrin MehranfardHossein RezazadehNepton SoltaniAzadesadat Hosseini DastgerdiMahtab Ghanbari RadMaedeh GhasemiPublished in: Advances in pharmacological and pharmaceutical sciences (2023)
supplement, comparable to insulin, via decreasing PARs expression, mitigating COX-2 activity, and decreasing collagen deposition could exert a potent gastroprotective effect against inflammation, ulcer, and fibrotic development in T2DM patients.
Keyphrases
- type diabetes
- poor prognosis
- end stage renal disease
- glycemic control
- ejection fraction
- chronic kidney disease
- newly diagnosed
- binding protein
- prognostic factors
- cardiovascular disease
- peritoneal dialysis
- insulin resistance
- diabetic rats
- anti inflammatory
- metabolic syndrome
- long non coding rna
- patient reported outcomes
- skeletal muscle
- young adults
- endothelial cells
- stress induced