Association of Gestational Thyroid Function and TPOAb Positivity with Postpartum Depression: a prospective cohort study and systematic literature review with meta-analysis.

There was no significant association of TPOAb positivity, TSH or FT4 with PPD. Our systematic review and meta-analysis revealed high heterogeneity of the current literature. Although TPOAb-positive women should be monitored for postpartum thyroiditis, our findings do not support routinely screening for PPD.