A fatal wound complication following sequential anti-angiogenesis, immune checkpoint inhibition and ultra-hypofractionated radiotherapy.
Miha OrazemCédric DraulansMathieu SpaasEric Van CutsemMarina DebeckerGert De MeerleerSabine TejparJeroen DekervelKarin HaustermansPublished in: Clinical journal of gastroenterology (2021)
This case represents an unusual fatal wound complication after palliative ultra-hypofractionated radiotherapy. Further research into synergistic effects of sequential radiotherapy and anti-angiogenesis therapy may provide an advantage in anticipating severe sequelae.
Keyphrases
- radiation therapy
- early stage
- locally advanced
- wound healing
- radiation induced
- endothelial cells
- high resolution
- vascular endothelial growth factor
- palliative care
- rectal cancer
- stem cells
- surgical site infection
- cancer therapy
- small cell lung cancer
- brain metastases
- mesenchymal stem cells
- advanced cancer
- cell therapy
- bone marrow
- drug delivery