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MyoMiner: explore gene co-expression in normal and pathological muscle.

Apostolos MalatrasIoannis MichalopoulosStéphanie DuguezGillian Butler-BrowneSimone SpulerWilliam John Duddy
Published in: BMC medical genomics (2020)
These co-expression analyses will help investigators to delineate the tissue-, cell-, and pathology-specific elements of muscle protein interactions, cell signaling and gene regulation. Changes in co-expression between pathologic and healthy tissue may suggest new disease mechanisms and help define novel therapeutic targets. Thus, MyoMiner is a powerful muscle-specific database for the discovery of genes that are associated with related functions based on their co-expression. MyoMiner is freely available at https://www.sys-myo.com/myominer.
Keyphrases
  • poor prognosis
  • binding protein
  • skeletal muscle
  • single cell
  • cell therapy
  • genome wide
  • emergency department
  • long non coding rna
  • bone marrow
  • transcription factor
  • dna methylation
  • stem cells
  • protein protein