Carcinoembryonic antigen-specific, fluorescent image-guided cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for metastatic colorectal cancer.
D P SchaapK S de ValkM M DekenR P J MeijerJ BurggraafAlexander L VahrmeijerM Kustersnull nullPublished in: The British journal of surgery (2020)
This multicentre pilot study investigated the role of peroperative carcinoembryonic antigen (CEA)-specific fluorescence imaging during cytoreductive surgery-hyperthermic intraperitoneal chemotherapy surgery in peritoneal metastasized colorectal cancer. A correct change in peritoneal carcinomatosis index (PCI) owing to fluorescence imaging was seen in four of the 14 included patients. The use of SGM-101 in patients with peritoneally metastasized colorectal carcinoma is feasible, and allows intraoperative detection of tumour deposits and alteration of the PCI. Augmented reality guidance.
Keyphrases
- fluorescence imaging
- minimally invasive
- coronary artery bypass
- photodynamic therapy
- percutaneous coronary intervention
- metastatic colorectal cancer
- end stage renal disease
- acute myocardial infarction
- coronary artery disease
- surgical site infection
- ejection fraction
- newly diagnosed
- locally advanced
- clinical trial
- antiplatelet therapy
- prognostic factors
- peritoneal dialysis
- atrial fibrillation
- randomized controlled trial
- st elevation myocardial infarction
- patients undergoing
- quantum dots
- squamous cell carcinoma
- radiation therapy
- high resolution
- patient reported outcomes
- left ventricular
- double blind
- metastatic renal cell carcinoma
- atomic force microscopy