The Effect of Safety Warnings on Antipsychotic Drug Prescribing in Elderly Persons with Dementia in the United Kingdom and Italy: A Population-Based Study.
Janet SultanaAndrea FontanaFrancesco GiorgianniAlessandro PasquaClaudio CricelliEdoardo SpinaGiovanni GambassiJelena IvanovicCarmen FerrajoloMariam MolokhiaClive BallardSamantha SharpMiriam SturkenboomSalvatore CrisafulliPublished in: CNS drugs (2018)
The 2004 warnings led to a reduction in the use of olanzapine and risperidone and increased the use of quetiapine/conventional APs in both countries. From 2009, the use of APs decreased in persons with dementia in the UK but not in Italy. Possible reasons for the difference in AP use between the two countries include a more proactive approach towards reducing the use of APs in the UK than in Italy.