The use of growth hormone therapy in adults with Prader-Willi syndrome: A systematic review.

Mikaela FrixouDiane VlekAngela K Lucas-HeraldLindsay KeirAndreas Kyriakou Mohamad Guftar Shaikh

Published in: Clinical endocrinology (2020)

These data suggest that GH is safe and well tolerated in adults with PWS, with evidence of improvement in body composition. Further longitudinal studies are still required to investigate the effects of GH on bone and cardiovascular health. Where GH is used in adults with PWS, this should be managed by a specialist multidisciplinary team with regular monitoring initiated.

Keyphrases

growth hormone
body composition
bone mineral density
resistance training
palliative care
quality improvement
electronic health record
big data
postmenopausal women
cross sectional
case report
soft tissue
stem cells
artificial intelligence
mesenchymal stem cells
cell therapy
data analysis