Antifungal Prophylaxis with Posaconazole versus Fluconazole in Children with Neutropenia Following Allogeneic Hematopoietic Stem Cell Transplantation: Single Center Experience.
Chayamon TakpraditChonthida WangkittikalSupattra RungmaitreeJassada BuaboonnamNattee NarkbunnamKamon PhuakpetNassawee VathanaKleebsabai SanpakitBunchoo PongtanakulPublished in: Journal of blood medicine (2021)
POS and FLU demonstrate comparable levels of effectiveness, safety, and tolerability as IFD prophylaxes for neutropenic children treated with allogeneic HSCT. Determination of the optimum POS dose and duration requires larger studies.
Keyphrases
- allogeneic hematopoietic stem cell transplantation
- candida albicans
- young adults
- acute lymphoblastic leukemia
- acute myeloid leukemia
- stem cell transplantation
- randomized controlled trial
- systematic review
- bone marrow
- open label
- low dose
- solid phase extraction
- molecularly imprinted
- high dose
- high resolution
- case control