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Probiotic Treatment of Ulcerative Colitis with Trichuris suis ova: A Randomized, Double-blinded, Placebo-controlled Clinical Trial (the PROCTO Trial).

Michelle V ProsbergSofie I HalkjærBobby LoChristina Bremerskov-KöserJohan F K F IlvemarkJakob Benedict SeidelinMalene F KristiansenAnja KortThomas KallemosePeter BagerFlemming BendtsenInge Nordgaard-LassenHanne S KapelHelene KringelChristian M O KapelAndreas M Petersen
Published in: Journal of Crohn's & colitis (2024)
Compared to placebo, Trichuris suis ova was not superior in achieving clinical remission at week 24 in ulcerative colitis or in achieving clinical Mayo score reduction, complete corticosteroid-free clinical remission or endoscopic remission. However, Trichuris suis ova treatment induced symptomatic temporary remission at week 12.
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